Pharmacodynamics and safety of intravenous pegaspargase during. Combine files into a single pdf, insert a pdf into another pdf, insert a clipboard selection into a pdf, or place insert a pdf as a link in another file. Powerpoint web apps is the online free version of powerpoint that has the new metro interface and features that you will find in the office 20 version. If your pdf is in a presentation format, the conversion should be no problem. Tell your doctor all medications and supplements you use. Open powerpoint and display the slide where you want to insert the pdf text. Drug preparation and administration hematologyoncology. Baxalta granted eu marketing authorization for oncaspar pegaspargase as a component of combination therapy in acute lymphoblastic leukaemia all all is a rare blood cancer that affects.
Immediately following the bolus dose administration, initiate a continuous infusion of integrilin. Click the image and it will be inserted into the slide. Save money on your ifosfamide injection prescription by switching to tevas fdaapproved generic version. The use of oncaspar in place of lasparaginase reduces the number of drug injections required, from 21 injections of lasparaginase to three injections with oncaspar over the 20week course of treatment. How to insert date time in powerpoint 2010 presentation. For further product information and current package insert, please visit. We report a tolerance induction strategy to prevent antigenspecific humoral immune responses to therapeutic proteins. Side effects of oncaspar pegaspargase, warnings, uses. Pegaspargase injection oncaspar side effects, medical. Although prior fda labeling submission requirements have been in the ms word and pdf formats, the fda now requires the package insert portion of. Oncaspar can be given by intramuscular injection or intravenous infusion. Insert pdf file content into a powerpoint presentation powerpoint. The fda previously approved oncaspar only for patients with all who were unable to receive the cancer drug lasparaginase because of an allergy. Tech support scams are an industrywide issue where scammers trick you into paying for unnecessary technical support services.
Sip3d package concepts multiple component packageinpackage packageonpackage powerpoint presentation. In the insert object box, select create from file, and then enter the pdf file location. Primary structure is the order or sequence of amino acid residues peptides are always written and named with the amino terminus on the left and the carboxy terminus on the right strong acid required to hydrolyse peptide bonds cysteine residues create disulfide bridges between chains this does not reveal primary structure dr. Show possession by adding s at the end of the word. Generic drug manufacturers must update their pm to ensure it aligns with the canadian reference product. Inhibit the production of certain clotting factors in the liver, e. P030 desensitization protocol for pegaspargase anaphylaxis. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that. Oncaspar can be administered through intramuscular im injection or intravenous iv infusion. If you go with this option, you probably want to keep the pdf file as a supporting document for your powerpoint presentation. It is ideal for presenting data contained within other. Do not mix reagents from different lots within a given test run. Common side effects include allergic reactions, blood clotting problems, high blood sugar, liver problems, pancreas inflammation, and blood clots in the brain.
Baxalta granted eu marketing authorization for oncaspar. For iv administration, reconstitute elspar by adding 5 ml sterile water for injection or sodium chloride injection to the 10,000 unit vial. Governorsgeneral from four countries brothersinlaw and their wives. A pdf document is filled with all kinds of content, including text or images, that you might want to import elsewhere. The package insert is also submitted in pdf and spl format. This study included three cohorts of pediatric leukemia patients treated upfront with pegaspargase. Pegaspargase oncaspar is a modified form of native e coli asparaginase in which the enzyme is covalently linked to polyethylene glycol. Combine or merge files into a single pdf, adobe acrobat dc. To bring you great quality, smallpdf has partnered with solid documents that offers the best conversion out there.
Consumer information about the medication pegaspargase injection oncaspar, includes side effects, drug interactions, recommended dosages, and storage information. Pegaspargase, sold under the trade name oncaspar, is a medication used in the treatment of acute lymphoblastic leukemia all. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to. Direct costs hospitalization, drug administration, allergic reactions management were derived from gazzetta ufficiale. It is not known if oncaspar passes into breast milk.
The diagrams consist of colored circular shapes for each p central idea being the marketing mix name. If the identification number is missing, or different from the stated number above, the strip should not be used. When using an intravenous infusion pump, administer integrilin undiluted directly from the 100ml vial. The quality of the pdf file is reduced with this method, but you can open the full pdf file by doubleclicking the image when viewing or editing in normal view. Not known whether pegaspargase is distributed into milk. For purpose of this study, the drug was given as a single intravenous dose. In this case, youll insert the entire pdf into the presentation as an object on a powerpoint slide, which you can open and view during presentation by selecting the pdf object. Each extended release tablet filmcoated tablet contains verapamil hydrochloride usp 240mg.
Convert pdf to powerpoint convert your pdfs to powerpoint. Winner of the standing ovation award for best powerpoint templates from presentations magazine. This will bring up header and footer dialog, enable date and time option, and beneath it choose a. For smaller volumes of oncaspar, the preferred route of administration is intramuscular. You can help protect yourself from scammers by verifying that the contact is a microsoft agent or microsoft employee and that the phone number is an official microsoft global customer service number.
Oncaspar, 48 patients 81% received all 3 planned doses of oncaspar, 6 10% received 2 doses, 4 7% received 1 dose, and 1 patient 2% did not receive the assigned treatment. Withdraw volume of reconstituted elspar containing calculated dose into sterile syringe. Work with the most accurate pdf to powerpoint converter. Changes may be necessary because of hypersensitivity reactions or availability. Using a pipette or psipette, pick up 14 colonies of identical morphology from the agar plate, either by suction or by successive touches. Due to the risk of hyperbilirubinaemia, it is recommended to monitor bilirubin levels at baseline and prior to each dose. The recommended dose of oncaspar is 2,500 ium 2 intramuscularly im or intravenously iv. Rules for compound nouns hyphenated nouns add to the confusion. Fulltext pdf desensitization to protein kinase inhibitors. This should be taken into account when considering the use of oncaspar in these patient populations. It is recommended to use young cultures 1824 hours old. How to insert a pdf into powerpoint online tech tips. Medlineplus information on pegaspargase a lay language summary of important information about this drug that may include the following.
Pegaspargase in the treatment of acute lymphoblastic leukemia. Detecting and treating asparaginaserelated toxicities in. Occasionally, the package insert component of product labeling for drugs that have received fda approval for commercial use is prefaced by prominent precautionary and warning summaries circumscribed by a rectangular border, commonly referred to as black box warnings, or, simply, boxed warnings. Baxter to buy oncaspar product portfolio from sigmatau. The marketing mix model, or marketing strategy also known as the 4 ps is widely used by marketers as a tool. The acquisition further accelerates the innovation capabilities and the commercial presence of baxter bioscience in growing oncology markets for rare and orphan diseases. Do not use if the oxygen indicator has turned blue or purple before opening the package see how suppliedstorage and handling 16.
Ppt drug education powerpoint presentation free to. A prospective study on drug monitoring of pegasparaginase and erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. If youre creating a microsoft powerpoint presentation, you can insert a pdf document by following these steps. Optical character recognition converts nonselectable text from scanned documents into editable office files. Dosage is based on your body size and response to treatment. The ndc code 0944381001 is assigned to oncaspar also known as. To form the plurals of hyphenated nouns, add s only to the first word. This medication is given by injection into a vein or a muscle by a health care professional. In this post we will look at how to insert datetime in the presentation. Extract media files from a powerpoint presentation by ryan johnson, itech if you ever find that you need to use the images, video, or audio clips from a powerpoint presentation, but you dont have access to the original files, theres a trick you can use to extract all the media from the powerpoint file.
To minimize the risk of complications when initiating iv therapy through. Shires new formulation of oncaspar gets approval in europe. Follow these steps to use adobe acrobat to combine or merge word, excel, powerpoint, audio, or video files, web pages, or existing pdfs. When utilized as a component of induction therapy for all, 1 dose of oncaspar achieved similar levels of asparagine depletion as 9 doses of native lasparaginase. When oncaspar is given by intramuscular injection the volume injected at one site should not exceed 2 ml in children and adolescents and 3 ml in adults.
During pregnancy, oncaspar should be used only when prescribed. One main difference that you may experiment while working with powerpoint web apps is the concept of themes and variants. Before we begin, you should be aware of the two ways you can do this. Read more about the prescription drug pegaspargase injection. Product information nordette tablets name of the medicine levonorgestrel and ethinyloestradiol chemically, ethinyloestradiol is 19nor17 pregna1,3,510trien20yne3,17diol and has. Study 2 is an ongoing, multifactorial design study in which all patients received oncaspar as a component of various. The products dosage form is injection, solution, and is administered via intramuscular. Definition from the nci drug dictionary detailed scientific definition and other names for this drug. Our modular, biomolecular approach involves engineering tolerizing. It is given by injection shot into the muscle or as an infusion in the hospital or clinic. It should be administered no more frequently than every 14 days.
Advanced office addin development with excel, word. Lyophilized oncaspar builds on more than a decade of data and research with liquid oncaspar, and with no change in dosing regimen, it offers a threetimes longer shelf life, said howard b. Inserting a pdf as an image is a quick way to present flat data in a noninteractive fashion. Antigenspecific immune responses to protein drugs can hinder efficacy and compromise safety because of drug neutralization and secondary clinical complications. Ppt heparin powerpoint presentation free to view id. In this session we will dive deep into the advanced clientspecific apis for building addins in excel, word, and powerpoint. Name of the medicinal product oncaspar solution for injection 2.
Withdraw the bolus doses of integrilinfrom the 10ml vial into a syringe. Oncaspar may interact with vincristine, prednisone, or methotrexate. Free powerpoint templates of the famous 4ps marketing mix and extended models. Engineered binding to erythrocytes induces immunological. Since many medicines can pass into breast milk and since, as a consequence, there is a risk of serious adverse reactions to oncasparfor the. The reconstituted solution contains 5,000 international units iuml. Pegaspargase pegasparjace destroys leukemia cancer cells in the first growth g 1 phase of cell life. Shires shpg marketing authorization application for a new dried formulation of its leukemia drug, oncaspar receives approval from the european commission. Often it is used together with anthracycline, vincristine, and prednisone. Types of anticoagulants inhibitors of clotting factor synthesis. Modified smile msmile is active in the treatment of extranodal. Modified smile msmile is active in the treatment of extranodal natural.
Interfere with blood clotting by blocking the activity of thrombin, e. Insert pdf content into your presentation either as a picture that shows on your slide, or as a document that you can open during your slide show. The governorgenerals car my brotherinlaws boat but. Fulltext pdf costeffectiveness of drugeluting stents in elderly patients with coronary artery disease. Insert pdf file content into a powerpoint presentation. See full prescribing information for 3,750 international units5 ml solution in a singleuse vial. Turn your pdf presentations to editable powerpoint ppt and pptx slideshows. The pdf file should be the first option within the insert dialog window. Pegaspargase is also being studied in the treatment of other types of cancer.
1471 993 110 1425 310 514 1235 1285 279 222 791 554 1045 205 1342 221 1227 199 297 1481 1118 430 270 1236 553 29 553 158 852 777 1078 1391 810 325 974 940 1185 810 629 1430 930 686